Global Idiopathic Pulmonary Fibrosis (IPF) Pipeline Analysis, 2016

IPF Pipeline Analysis

The study analyzed that the IPF pipeline comprised of 97 therapeutic candidates, of which 15 are in Phase II stage of development. The lack of complete cure for IPF fuels the extensive research and development for the IPF therapeutic. Various drugs are being developed as novel and promising therapeutics for the treatment of IPF.

Insights on pipeline segments

As per the findings of research, it was found that around 9% IPF candidate target chemokine, 7% target integrin and 6% of the product candidates target G-protein couple receptor. Other targets comprising 78% of candidates of IPF pipeline include, but not limited to, autotaxin, connective tissue growth factor-associated, fibroblast growth factor, lysyl-oxidase like protein 2 and tissue growth factor beta. Around 55% pipeline therapeutic candidates of IPF are being developed to be administered by oral route, 20% by inhalation route, 12% by intravenous route and 8% by subcutaneous route.

Phase III stage of development consist of only one IPF drug

Thrombomodulin Alfa (ART-123) is under Phase III stage of development by Asahi Kasei Pharma Corporation for the treatment of IPF. It is already marketed in Japan under the name of Recomodulin for the treatment of disseminated intravascular coagulation. Thrombomodulin Alfa is a soluble recombinant human thrombomodulin and inhibits the coagulation process by accelerating the activation of protein C by thrombin. The drug candidate is administered by intravenous route.

Phase II stage of development is crowded with number of promising drugs

There are total 15 drug candidates in Phase II stage of development for the treatment of IPF. GLPG1690 is under Phase II stage of development by Galapagos NV for the treatment of IPF. The drug candidate targets lysophosphatidic acid 1 (LPA1) receptor also known as autotaxin and inhibits its action. The company plans to disclose the Phase II topline results for IPF in the first half of 2017. In February 2015, Galapagos NV released the Phase I study results for GLPG1690 (NCT02179502). GLPG1690 proved to be safe and well-tolerated over a wide dose range in healthy volunteers. The drug candidate showed favorable pharmacokinetic and pharmacodynamic profile. In this trial, GLPG1690 demonstrated the ability to reduce plasma lipid lysophosphatidic acid (LPA) levels on a sustained basis, implying ATX engagement.

More than 10 drug candidates got Orphan Drug Designation (ODD)

U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) granted ODD to more than 10 drugs. As per the FDA, its Office of Orphan Products Development (OOPD) mission is to advance the evaluation and development of products (drugs, biologics, devices, or medical foods) that demonstrate promise for the diagnosis and/or treatment of rare diseases or conditions. Tipelukast, also known as MN-001, is under Phase II stage of development by MediciNova, Inc. for the treatment of IPF. The drug was granted ODD for the treatment of IPF, which will provide MediciNova with seven years of marketing exclusivity if it is approved for IPF. Some of the key players developing drugs candidates for the treatment of IPF are Bristol-Myers Squibb Company, F. Hoffmann-La Roche Ltd., Merck & Co., Inc., Global Blood Therapeutics, Inc., Asahi Kasei Corporation, Beijing Tide Pharmaceutical Co., Limited, FibroGen, Inc., Chong Kun Dang Pharmaceutical Corp., Galapagos NV, Kadmon Holdings, Inc., MediciNova, Inc., and Promedior, Inc.

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Automotive Sunroof System Market Expected to Witness Fastest Growth in North America During 2016 – 2022

Automotive Sunroof Market Trends

The global automotive sunroof market was valued at $4,924.5 million in 2015, and it is expected to grow at a CAGR of 10.9% during 2016 – 2022. The factors driving the growth of the global market includes growing need to control light inside vehicle, growing demand for premium cars, and greater glass surface area in automobiles, including larger sunroofs. Additionally, the development of technology for reducing cost and expanding functionality of sunroof glasses and increasing consumer preference towards automotive sunroof vehicles in developing nations are expected to further propel the global demand of automotive sunroof.

Automotive sunroof refers to any roof opening in vehicle, such as one with a retractable metal panel. Modern sunroof consists of around 200 parts, and vehicle maker now use them and other roof system to help differentiate product offering to customers. Consumers now expect an increasingly high level of comfort in their cars, particularly where air conditioning and sun roof are concerned. Such equipment is no longer the exclusive domain of luxury cars. As the market is becoming increasingly competitive, vehicle makers are using sunroofs and other roof systems to help differentiate the product offering to customers. The demand for sunroof as an after sales market has also contributed to the growth of the global automotive sunroof market. The growing alternative fuel vehicle segments have forced the automotive innovators to develop sunroofs with built-in solar cells, which provide power to vehicles. The preference of car involving a sunroof is a major trend witnessed in the automotive sunroof market during the last few years.

In 2015, Europe held the largest share in the global automotive sunroof market. The automotive sunroof market in the region is anticipated to grow significantly during the forecast period. The major reasons behind the growth of the automotive sunroof market are strict environment regulations, increasing demand for electric vehicles, and growing need to control light inside vehicle. Asia-Pacific held the second largest share in the global market and it is also expected to witness the fastest growth during the forecast period. The demand for automotive sunroof in Asia-Pacific is expected to increase rapidly, owing to growing base of automotive industry, and increasing demand for luxurious and premium cars. Moreover, the governments of emerging economies of China, India, South Korea, and Thailand are providing incentives and industry friendly environment, which is attracting huge investment from automotive manufacturer for setting up new manufacturing plants in the region.

Some of the major companies operating in the global automotive sunroof market include Webasto SE, Johnan America, Inc., Automotive Sunroof Company, Nippon Sheet Glass Co. Ltd., Yachiyo Industry Co., Ltd., Corning Inc., Meritor Inc., Aisin Seiki Co., Ltd., Inteva Products, LLC, and Inalfa Roof Systems Group B.V.

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Europe Lead the Global Point-of-Care Ultrasound (PoCUS) Device Market Due to Technological Advancements and Aging Population

PoCUS Device Market

The global point of care (PoCUS) device market is expected to grow at a CAGR of 6.9% during 2015 – 2025. The growth of the global market is largely driven by increasing awareness about the benefits of portable ultrasound devices in point-of-care. Several beneficial features such as size, weight, performance and battery life of portable ultrasound devices are increasing their popularity among healthcare providers. Healthcare providers and patients are getting aware about these benefits of portable ultrasound devices in point-of-care. This has created huge traction in the diagnostic imaging industry for developing portable ultrasound devices for point-of-care. Different companies are investing huge capital for miniaturization of ultrasound devices for their efficient use in point-of-care. Some of the other factors driving the growth of the global market include prevalence of chronic diseases, and technological advancements. Increasing penetration of PoCUS device manufacturers in emerging economies is expected to create ample growth opportunities for the global market. However, lack of skilled sonographers and stringent regulatory requirements are the key barriers for the growth of the global market.

Among the two types of PoCUS devices, the diagnostic PoCUS device segment was the larger contributor to the global PoCUS devices revenue in 2015; whereas, therapeutic PoCUS device is expected to witness the higher growth during the forecast period. Increasing adoption of therapeutic PoCUS devise for the treatment of musculoskeletal disorders is the major factor driving the growth of therapeutic PoCUS device market. Therapeutic PoCUS devices helps to relief pain and inflammation, reduce muscle spasm, speed healing and increases range of motion.

Among the different applications, the largest revenue was generated from the sale of PoCUS devices point-of-care cardiology in 2015. The non-invasive characteristics of PoCUS, high incidence of cardiac diseases, growing geriatric population and increasing demand from home care and ambulatory settings are the key driving factors for the application segment.

Some of the players operating in the global market include Hitachi Ltd., Toshiba Medical Systems Corporation, Siemens AG, Koninklijke Philips N.V., Esaote SpA, General Electric Company, Samsung, Mindray Medical International Limited, FUJIFILM Holdings Corporation, and Analogic Corporation.

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North America Accounts for the Largest Animal Pharmaceuticals Market Due to Large Consumption of Meat and Milk Products

Animal Pharmaceuticals market

The growth of the global market is largely driven by increasing consumption of meat and milk, and increasing zoonotic and food borne diseases. Due to growing health concern of related animals and their increasing number, the healthcare expenses in farms are surging globally. Animal farms are increasing globally, due to growing demand for protein rich foods, such as milk, eggs and meat. Increasing trend of pet adoption is another key factor driving the growth of the global market. The declining research and development productivity and growth of generic and OTC drugs for animal care are the key trend witnessed in the global market. The declining research and development productivity is leading to the maturity of animal pharmaceutical product portfolio. The fewer new chemical entity approvals are limiting the opportunities for key manufacturers to expand their portfolio in animal pharmaceuticals market. The low productivity of research and development increases the competition among the key manufacturers.

Among the different types of animal pharmaceutical products, the ectoparasiticides generated largest revenue in the global animal pharmaceuticals market in 2015. High prevalence of animals affected with ectoparasites is the key factor driving the growth of the ectoparasiticides market. The bronchodilators market would witness fastest growth during the forecast period.

Based on animal type, the largest revenue was generated from the sales of animal pharmaceuticals for companion animals in 2015. Whereas, the animal pharmaceuticals market for production animals would witness faster growth during the forecast period. Increasing awareness regarding the livestock related diseases is the key reason behind the higher growth of the animal pharmaceuticals market for production animals.

Some of the key players operating in the global market include Merck & Co. Inc., Vetoquinol S.A., Zoetis Inc., Virbac SA, Boehringer Ingelheim GmbH, Perrigo Company plc, Eli Lilly and Company, Sanofi and Bayer AG.

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Germany Cards and Payments Market Analysis, Size, Development and Forecast to 2020

cards-and-payments-market

The research report provides in depth analysis and insights into the Germany Cards and Payments Market including, strategies deployed by banks to market debit and credit cards and competitive landscape (card issuers in the country) for both debit cards and credit cards. The study includes 3 years historical market size and 6 years market forecast in terms of number of cards, value and volume of transactions processed through these cards, and other key metrics. The report also provides information on the key industry trends, major schemes, banks and detailed segmentation of card and payment industry. The research report is a new offering from the company’s Financial Services domain, and leveraged from the company’s existing cards and payments database of 50+ countries.

 

Germany is the largest country in Western Europe, with a total population of 81.1 million in 2014 (of which 82.3% were adults), which is significantly ahead of France, Turkey and the UK. There are 1.6 cards per person in the country, which is close to the European average number; in comparison, Norway and France have the highest and lowest levels of card penetration in Europe. The German GDP per capita increased from EUR 34,211 in 2012 to EUR 35,951 in 2014. GDP per capita is likely to increase further over the forecast period to EUR 41,672 in 2020.This increase in GDP per capita income levels is expected to increase the scope of payment cards use over the forecast period.

In Germany, the debit card dominates the payment cards market in terms of number of cards in circulation. Debit cards accounted for 76.8% of the total number of payment cards in circulation in 2014. Growth in the German debit card market has been relatively weak in terms of number of cards in issue, witnessing a CAGR of -1.3% during 2012-2014. Average debit card transaction value decreased from EUR 103.9 in 2012 to EUR 98.3 in 2014, at a CAGR of -2.7%. The average transaction value is also expected to decline at a CAGR of -1.2% during the period 2015-2020.The frequency of debit card usage grew at a CAGR of 8.8% during 2012-2014. Some of the key players in the debit cards market include BVR, Targobank, and Commerzbank.

In Germany, the charge cards are largely used by consumers at POS terminals for retail purchases rather than cash withdrawals at ATMs. In 2014, the number of charge card transactions at POS terminals accounted 95% of the total charge card transactions in the country.

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U.S. Cards and Payments Market Trends, Size, Share, Development and Forecast to 2020

cards-and-payment-market

The research report provides in depth analysis and insights into the U.S. Cards and Payments Market including, strategies deployed by banks to market debit and credit cards and competitive landscape (card issuers in the country) for both debit cards and credit cards. The study includes 3 years historical market size and 6 years market forecast in terms of number of cards, value and volume of transactions processed through these cards, and other key metrics. The report also provides information on the key industry trends, major schemes, banks and detailed segmentation of card and payment industry. The research report is a new offering from the company’s Financial Services domain, and leveraged from the company’s existing cards and payments database of 50+ countries.

In terms of number of cards in circulation, the U.S. payment cards market grew at a CAGR of 4.5% during the period 2012-2014 and it is expected to further grow at a CAGR of 1.3% over the period 2015-2020. The growth of the card market in the country was supported by the increase in GDP per capita of U.S., which increased from USD 51,384 in 2012 to USD 54,369.8 in 2014. The GDP per capita is further expected to reach USD 67,064.3 by 2020. This increase is expected to result in increased cards usage over the forecast period. The U.S. population grew from 314.4 million in 2012 to 319 million in 2014, and is expected to reach 332.4 million by 2020. The increase in population is expected to encourage the growth of cards in circulation and card spending over the forecast period.

The sustained increase in POS terminals in the U.S. reflects growth in the POS acceptance network. The number of POS terminals recorded a CAGR of 3.1% over 2012–14. The POS penetration rate in 2014 was 34.3 people per POS terminal.

In U.S., the debit card segment dominates the payment cards market in terms of number of cards in circulation. Debit cards accounted for 53.2% of the total number of payment cards in circulation in 2014. In debit card segment, Bank of America was the leading card issuer in terms of the number of cards in circulation, in 2014. The transaction value of debit card at POS terminals accounted for 77.7% of the aggregate debit card transaction value in 2014. Some of the key players in the debit cards market include Bank of America, Wells Fargo and JP Morgan Chase.

Over the period 2012–2014 charge cards recorded a CAGR of 4.1%. However, it is expected that the charge cards market will experience a CAGR of 1.8% over 2015–2020. The average charge card transaction value decreased from USD 108.7 in 2012 to USD 106.0 in 2014, at a CAGR of -1.2%. The average transaction value is anticipated to grow at a CAGR of 0.4% during the period 2015-2020.

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Turkey Cards and Payments Market Forecasted to Grow at a Healthy Rate During 2015-2020

cards-and-payment-market

The report includes the market size and forecast of the Turkish cards and payments market for the period 2012 to 2020 (in terms of number of cards, value and volume of transactions processed through these cards), along with the key industry trends, major schemes, banks and card market by customer segments. The report also includes competitive landscape (card issuers in the country) for both debit cards and credit cards.

The card payments market in Turkey grew at a healthy pace during the period 2012 – 2014, both in terms of volume and value. Some of the factors fueling the growth of the market are payment infrastructure modernization, growing number of cards in circulation, and the benefits offered to debit card and credit card holders by the card issuers. In terms of number of transactions, the overall Turkish card market is expected to grow at a CAGR of 7.7% during 2015-2020.

In Turkey, the debit cards dominate the total card payments market in terms of number of cards in circulation. In 2014, debit cards accounted for 65.2% of total cards in circulation. Debit card also dominated the Turkish card payments market in terms of number of transactions and value of transactions. By scheme, Visa dominates the number of debit cards in circulation, followed by MasterCard in 2014.

The credit cards transaction value reported at POS terminals was greater than at ATMs. The credit cards transaction value at POS terminals represented 91.5% of the total credit cards transaction value in 2014. Widespread acceptance of credit cards by merchants, the growing consumer demand, and increase in the number of POS terminals contributed to the growth of the credit card segment in Turkey.

Consumer preference for cashless payments enables growth of card payments. Banks and card issuers have implemented different pricing and marketing strategies to encourage consumers to increase card payments rather than paying in cash. Common strategies used by banks and card issuers are product discounts and reward points. As the internet users have increased, it has contributed to the growth of e-commerce in Turkey, which has directly influenced the growth of cards and payments industry in the country. The credit and debit cards dominate e-commerce because of attractive promotional offers such as discounts and free shipping. As increased number of retailers moving their business operations online to increase market share and to expand their customer base, the e-commerce growth is expected to continue in Turkey.

Some of the key players in the Turkish debit card market include Ziraat, VakifBank, Yapı Kredi, Garanti and Finansbank. The key players in the credit card market include Yapı Kredi, Garanti, Finansbank, Ziraat and VakifBank. Yapı Kredi was the leading bank in credit card segment in 2014, in credit cards in circulation.

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Singapore Cards and Payments Market Analysis, Size, Development and Forecast to 2020

cards-and-payments-market-by-ps-market-research

The research report provides in depth analysis and insights into the Singapore Cards and Payments Market including, strategies deployed by banks to market debit and credit cards and competitive landscape (card issuers in the country) for both debit cards and credit cards. The study includes 3 years historical market size and 6 years market forecast in terms of number of cards, value and volume of transactions processed through these cards, and other key metrics. The report also provides information on the key industry trends, major schemes, banks and detailed segmentation of card and payment industry. The research report is a new offering from the company’s Financial Services domain, and leveraged from the company’s existing cards and payments database of 50+ countries.

 

The Singapore payment card market grew at a CAGR of 3.3% in terms of number of cards in circulation, during the period 2012-2014. The country had a high penetration of 3.8 cards per person in 2014, with number of cards in circulation reaching 21.3 million and total population of the country being 5.6 million.

In Singapore, the debit cards dominate the payment card market in terms of number of cards in circulation. In 2014, the debit cards accounted for more than half of the total number of cards in circulation in Singapore. Some of the key players in the debit cards market include DBS Bank, United Overseas Bank, OCBC, Citibank and Standard Chartered Bank. By scheme, the number of debit cards in circulation was dominated by NETS in 2014. NETS is an online debit payment system jointly owned by DBS Bank, OCBC Bank and United Oversea Bank. DBS Bank was the leading bank in terms of the number of debit cards in 2014.

The charge card segment represents a small portion of the Singaporean pay later card market but it is expected to gain momentum due to expected growth in the volume of high net worth individuals during the period 2015 – 2020.

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Peru Cards and Payments Market Trends, Development, Growth and Forecast to 2020

cards-and-payments-market

The research report provides in depth analysis and insights into the Peru Cards and Payments Market and competitive landscape (card issuers in the country) for both debit cards and credit cards. The study includes 3 years historical market size and 6 years market forecast in terms of number of cards, value and volume of transactions processed through these cards, and other key metrics. The report also provides information on the key industry trends, major schemes, banks and detailed segmentation of card and payment industry. The research report is a new offering from the company’s Financial Services domain, and leveraged from the company’s existing cards and payments database of 50+ countries.

In Peru, the debit cards dominate the card payments market in terms of number of cards in circulation. Debit card also dominated the Peru card payments market in terms of number of transactions and value of transactions. Average debit card transaction value increased from PEN 362.9 in 2012 to PEN 409.0 in 2014, at a CAGR of 6.2%.

The credit card penetration in Peru per 100 inhabitants increased from 19 in 2012 to 21 in 2014 and it is further expected to increase during the forecast period. The transaction value of credit cards reported at POS terminals was greater than at ATMs. The average credit card transaction value in Peru declined marginally from PEN 375.8 in 2012 to PEN 368.1 in 2014, at a CAGR of -1.0%. The average transaction value is anticipated to decrease during the forecast period.

Some of the key players in the debit cards market include Banco de Crédito del Perú, BBVA Continental Scotiabank, Midbanco, Banco Financiero and Banco Falabella Peru. Banco de Crédito del Perú was the leading bank in terms of the number of debit cards in 2014. Some of the key players in the credit card market of Peru include Banco Falabella Peru, Banco de Crédito del Perú, Interbank, BBVA Continental and Scotiabank. In the credit card segment, Banco Falabella Peru was the leading bank in 2014, in terms of number of credit cards in circulation.

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Train Control and Management System Market Expected to Witness Fastest Growth in North America During 2016 – 2022

train-control-and-management-system-market

The global train control and management system market was valued at $2,031.6 million in 2015, and it is expected to grow at a CAGR of 8.2% during 2016 – 2022. Increasing population and urbanization, growing demand for safe and comfortable rapid transit solutions in developed as well as developing regions, and stringent emission control norms are expected to drive the demand for TCMS over the forecast period. The global demand for rail vehicles is fueled by the increasing population in urban areas, where the current transportation infrastructure is turned out to be insufficient. Increase in the development of the infrastructure network is expected to drive the demand for rail vehicles. Rapid transit vehicles are gaining popularity due to their rapid mobility and high seating capacity. In comparison to developing regions, developed regions such as Europe and North America have well established infrastructure for rapid transit vehicles such as subways, monorails and metros. To reduce traffic congestion on roads, government of developing nations such as China, India, Singapore and Thailand are investing in rapid transport system. The increasing demand for rapid transit vehicles in developing regions is expected to boost the demand for TCMS during the forecast period.

Among the various components of TCMS, the vehicle control unit held the largest share in the global TCMS market in 2015. The market of train control and management system was the largest in metros & high speed train segment in 2015, compared to other train types. Globally, communication-based train control solution (CBTC) was the largest segment, based on solution of train control and management system in 2015.

In 2015, Europe accounted for the largest share in the global train control and management system market; whereas the market in North America is expected to grow at the fastest rate, during the forecast period. The major reason for the growth of the market in the North America includes increasing investments in technology upgradation and rapid transit solution. Moreover, government has started several high speed train projects in U.S., which are expected to be commissioned by 2020. This in turn, is expected to fuel the market of TCMS in North America during the forecast period.

Some of the major players operating in the global train control and management system market include Alstom SA, Bombardier Inc., Toshiba Corporation, Siemens AG, Hitachi Ltd., CAF, Mitsubishi Electric Corporation, EKE Group and Strukton Rail.

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